Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177204 | 0.86 | TSHR (0.57) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL28171537 | 0.85 | ALDH1A1 (0.53) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL7035059 | 0.83 | MAPK1 (0.53) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL27552505 | 0.81 | NPSR1 (0.36) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL15994168 | 0.81 | TSHR (0.55) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL11291473 | 0.80 | ALDH1A1 (0.62) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL878321 | 0.79 | TSHR (0.53) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL15659596 | 0.79 | TSHR (0.53) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL27850590 | 0.79 | TSHR (0.53) | TSHRLMNAGAAALDH1A1MEN1 | |
| SCHEMBL6792424 | 0.79 | TSHR (0.49) | TSHRLMNAGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660022-B1 | AGENT FOR COLOURING KERATIN FIBRES | HFC PRESTIGE INT HOLDING SWITZERLAND S A R L (CH) | 2017-04-12 | — | — | EP | claimed |
| US-20090056039-A1 | DYE-CONTAINING PELLETS FOR COLORING KERATIN FIBERS | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2009-03-05 | — | — | US | claimed |
| US-20170273881-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | ALFA PARF GROUP S.P.A. (IT) | 2017-09-28 | — | — | US | disclosed |
| US-20160250118-A1 | METHOD AND COMPOSITION TO REMODELLING KERATINIC FIBER | ALFA PARF GROUP S.P.A. (IT) | 2016-09-01 | — | — | US | disclosed |
| WO-2016026710-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | ALFA PARF GROUP S.P.A. (IT) | 2016-02-25 | — | — | WO | disclosed |
| US-7431742-B2 | Hair coloring kits and methods of use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1877031-A2 | HAIR COLOURING KITS AND METHODS OF USE THEREOF | The Procter and Gamble Company (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070251025-A1 | Hair coloring kits and methods of use thereof | THE PROCTER & GAMBLE COMPANY | 2007-11-01 | — | — | US | disclosed |
| US-20070017039-A1 | Methods of merchandising hair color refresher products | PROCTER & GAMBLE COMPANY, THE | 2007-01-25 | — | — | US | disclosed |
| WO-2006118942-A2 | HAIR COLOURING KITS AND METHODS OF USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2006-11-09 | — | — | WO | disclosed |
| EP-1140917-B1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2003-03-26 | — | — | EP | disclosed |
| US-6451802-B1 | S-oxide lipid lowering compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-09-17 | — | — | US | disclosed |
| EP-1140917-A1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037463-A1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-06-29 | — | — | WO | disclosed |
| US-4490530-A | ANTIFUNGAL, ANTIBACTERIAL | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-12-25 | — | — | US | disclosed |
| EP-0006711-B1 | HETEROCYCLIC DERIVATIVES OF (4-PHENYLPIPERAZIN-1-YL-ARYLOXYMETHYL-1,3-DIOXOLAN-2-YL)-METHYL-1H-IMIDAZOLES AND 1H-1,2,4-TRIAZOLES, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-10-26 | — | — | EP | disclosed |
| US-4368200-A | BACTERICIDES, FUNGICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-01-11 | — | — | US | disclosed |
| US-4267179-A | AS FUNGICIDES AND BACTERICIDES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-05-12 | — | — | US | disclosed |
| EP-0006711-A1 | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)-methyl-1H-imidazoles and 1H-1,2,4-triazoles, processes for preparing them and compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250118-A1 | METHOD AND COMPOSITION TO REMODELLING KERATINIC FIBER | KRT18, FABP2, CPT1A | TSHR 2595/4885LMNA 176/4885GAA 4868/4885 |
| US-20170273881-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | KRT18, GRHPR, CUTA | TSHR 4753/4885LMNA 697/4885GAA 605/4885 |
| US-20070251025-A1 | Hair coloring kits and methods of use thereof | COXFA4L2, SQOR, GPX4 | TSHR 3700/4885LMNA 1608/4885GAA 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.