Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182467 | 0.87 | ALDH1A1 (0.57) | MEN1ALDH1A1CRHBPKMT2AATM | |
| SCHEMBL15397513 | 0.84 | P2RX1 (0.39) | MMP1RAB9AMEN1ALDH1A1CRHBP | |
| SCHEMBL1973255 | 0.84 | MMP1 (0.39) | MMP1RAB9AMEN1ALDH1A1CRHBP | |
| SCHEMBL1973258 | 0.84 | MMP1 (0.39) | MMP1RAB9AMEN1ALDH1A1CRHBP | |
| SCHEMBL15397511 | 0.84 | P2RX1 (0.39) | MMP1RAB9AMEN1ALDH1A1CRHBP | |
| SCHEMBL1973054 | 0.84 | P2RX1 (0.40) | MMP1RAB9AMEN1ALDH1A1CRHBP | |
| SCHEMBL1973049 | 0.84 | P2RX1 (0.40) | MMP1RAB9AMEN1ALDH1A1CRHBP | |
| SCHEMBL21247872 | 0.82 | ALDH1A1 (0.67) | RAB9AMEN1ALDH1A1CRHBPKMT2A | |
| SCHEMBL439543 | 0.81 | CA1 (0.60) | RAB9AALDH1A1TGM2ABCG2CA1 | |
| SCHEMBL9264299 | 0.81 | L3MBTL1 (0.56) | RAB9AMEN1ALDH1A1CRHBPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771357-B2 | ALXR agonist compound | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-09-26 | — | — | US | disclosed |
| US-20160145249-A1 | ALXR AGONIST COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145249-A1 | ALXR AGONIST COMPOUND | MRGPRX2, MRGPRX1, MRGPRX4 | MMP1 324/4885RAB9A 3441/4885MEN1 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.