Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10963461 | 0.84 | LMNA (0.58) | LMNASMN1; SMN2POLBKDM4EMAPK1 | |
| SCHEMBL29478461 | 0.80 | LMNA (0.58) | LMNASMN1; SMN2POLBKDM4EMAPK1 | |
| SCHEMBL10967060 | 0.76 | RXFP1 (0.54) | LMNASMN1; SMN2POLBKDM4ERXFP1 | |
| Hydrochloric Acid SCHEMBL10554676 | 0.74 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2POLBKDM4ERXFP1 | |
| SCHEMBL10768492 | 0.74 | LMNA (0.78) | LMNASMN1; SMN2POLBKDM4ERXFP1 | |
| SCHEMBL11883059 | 0.73 | LMNA (0.52) | LMNASMN1; SMN2POLBKDM4EMAPK1 | |
| SCHEMBL683975 | 0.73 | LMNA (0.65) | LMNASMN1; SMN2POLBKDM4EMAPK1 | |
| SCHEMBL10970100 | 0.73 | LMNA (0.64) | LMNASMN1; SMN2POLBKDM4ERXFP1 | |
| SCHEMBL10063431 | 0.73 | LMNA (0.80) | LMNASMN1; SMN2POLBKDM4ERXFP1 | |
| Dyphylline SCHEMBL1816552 | 0.73 | LMNA (1.00) | LMNASMN1; SMN2POLBKDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049494-B1 | ESTERS OF 7-HYDROXYALKYL-1,3-DIMETHYL XANTHINES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS LIPID DIMINISHERS | King Consult GmbH (DE) | 1985-04-17 | — | — | EP | claimed |
| EP-0049494-B1 | ESTERS OF 7-HYDROXYALKYL-1,3-DIMETHYL XANTHINES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS LIPID DIMINISHERS | King Consult GmbH (DE) | 1985-04-17 | — | — | EP | disclosed |