Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diniprofylline SCHEMBL2108045 | 0.89 | LMNA (0.55) | LMNASMN1; SMN2POLBRXFP1GAA | |
| Diniprofylline SCHEMBL30035984 | 0.89 | LMNA (0.55) | LMNASMN1; SMN2POLBRXFP1GAA | |
| SCHEMBL11389921 | 0.86 | LMNA (0.57) | LMNASMN1; SMN2RXFP1GAAALDH1A1 | |
| Etofylline Nicotinate SCHEMBL1649975 | 0.85 | ADORA2B (0.64) | LMNASMN1; SMN2RXFP1GAAALDH1A1 | |
| SCHEMBL10970102 | 0.82 | LMNA (0.56) | LMNASMN1; SMN2POLBRXFP1GAA | |
| SCHEMBL25295543 | 0.80 | LMNA (0.56) | LMNASMN1; SMN2RXFP1GAAL3MBTL1 | |
| SCHEMBL30563571 | 0.80 | LMNA (0.56) | LMNASMN1; SMN2RXFP1GAAL3MBTL1 | |
| SCHEMBL10967060 | 0.80 | RXFP1 (0.54) | LMNASMN1; SMN2POLBRXFP1GAA | |
| SCHEMBL11389732 | 0.79 | PDE1A (0.55) | LMNASMN1; SMN2RXFP1GAAALDH1A1 | |
| Xanthinol SCHEMBL121655 | 0.78 | LMNA (1.00) | LMNASMN1; SMN2POLBRXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049494-B1 | ESTERS OF 7-HYDROXYALKYL-1,3-DIMETHYL XANTHINES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS LIPID DIMINISHERS | King Consult GmbH (DE) | 1985-04-17 | — | — | EP | claimed |