Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthinol SCHEMBL29388798 | 0.88 | LMNA (0.61) | LMNASMN1; SMN2RXFP1POLBKDM4E | |
| SCHEMBL10963461 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2RXFP1POLBKDM4E | |
| Theofibrate SCHEMBL3960649 | 0.84 | ADORA2B (0.60) | LMNASMN1; SMN2RXFP1POLBALDH1A1 | |
| Theofibrate SCHEMBL49272 | 0.84 | ADORA2B (0.60) | LMNASMN1; SMN2RXFP1POLBALDH1A1 | |
| Xanthinol SCHEMBL121656 | 0.75 | LMNA (0.73) | LMNASMN1; SMN2RXFP1POLBKDM4E | |
| Theofibrate SCHEMBL28085094 | 0.74 | LMNA (0.51) | LMNASMN1; SMN2RXFP1ALDH1A1MAPK1 | |
| SCHEMBL10963455 | 0.73 | LMNA (0.60) | LMNASMN1; SMN2RXFP1POLBKDM4E | |
| SCHEMBL11460190 | 0.72 | OPRK1 (0.55) | LMNASMN1; SMN2RXFP1ALDH1A1L3MBTL1 | |
| Acefylline Clofibrol SCHEMBL2110473 | 0.71 | MAPK1 (0.61) | LMNASMN1; SMN2RXFP1POLBL3MBTL1 | |
| SCHEMBL29478461 | 0.68 | LMNA (0.58) | LMNASMN1; SMN2RXFP1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3801578-A | 7-(2-HYDROXY-3-(N-METHYL-2-HYDROXY-ETHYLAMINO)-PROPYL)-THEOPHYLLINE-2-(4-CHLOROPHENOXY)-ISOBUTYRATE | CHINOIN GYOGYSZER ES VEGYESZET | 1974-04-02 | — | — | US | disclosed |