Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576277 | 0.88 | SSTR4 (0.38) | SSTR4SLC6A4SLC6A2RENSLC6A3 | |
| SCHEMBL1095976 | 0.87 | CCR5 (0.39) | — | |
| SCHEMBL1097414 | 0.82 | CCR5 (0.37) | SSTR4 | |
| SCHEMBL1096491 | 0.82 | REN (0.36) | SSTR4SLC6A4SLC6A2RENSLC6A3 | |
| SCHEMBL1096039 | 0.82 | DPP4 (0.34) | — | |
| SCHEMBL3570472 | 0.81 | SSTR4 (0.38) | SSTR4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4067653 | 0.76 | SSTR4 (0.41) | SSTR4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1095954 | 0.75 | SSTR4 (0.35) | SSTR4SLC6A4SLC6A2RENSLC6A3 | |
| SCHEMBL3576110 | 0.74 | CCR5 (0.38) | SSTR4SLC6A2SLC6A3 | |
| SCHEMBL1094614 | 0.71 | ESR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153658-B2 | Piperidine derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2012-04-10 | — | — | US | disclosed |