Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | AKT1 | P31749 | 13/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097414 | 0.94 | CCR5 (0.37) | CCR5AKT1RPS6KB1 | |
| SCHEMBL3576110 | 0.88 | CCR5 (0.38) | CCR5AKT1RPS6KB1 | |
| SCHEMBL1096492 | 0.87 | SSTR4 (0.33) | — | |
| SCHEMBL1095974 | 0.82 | CCR5 (0.39) | CCR5AKT1RPS6KB1 | |
| SCHEMBL3570815 | 0.81 | RPS6KB1 (0.38) | CCR5AKT1RPS6KB1 | |
| SCHEMBL1096778 | 0.80 | CCR5 (0.39) | CCR5 | |
| SCHEMBL4067653 | 0.80 | SSTR4 (0.41) | — | |
| SCHEMBL1097046 | 0.76 | CCR5 (0.37) | CCR5AKT1RPS6KB1 | |
| SCHEMBL1096262 | 0.75 | REN (0.37) | — | |
| SCHEMBL1094614 | 0.74 | ESR1 (0.33) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153658-B2 | Piperidine derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2012-04-10 | — | — | US | disclosed |