Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.59 |
| ▸ | PGR | P06401 | 6/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965356 | 1.00 | NR3C1 (0.59) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL11127166 | 0.92 | PGR (0.68) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL11126077 | 0.92 | PGR (0.68) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL11127163 | 0.92 | PGR (0.68) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL6859039 | 0.87 | CYP3A4 (0.61) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL6859043 | 0.87 | CYP3A4 (0.61) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL11583983 | 0.87 | NR3C1 (0.67) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL11583987 | 0.87 | NR3C1 (0.67) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL7596820 | 0.85 | PGR (0.61) | NR3C1CYP3A4PGRHIF1AABCB11 | |
| SCHEMBL11119966 | 0.85 | NR3C1 (0.67) | NR3C1CYP3A4PGRHIF1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555507-A | Novel 6, 16-dimethylcorticoids, their preparation and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| EP-0100874-A2 | 6,16-Dimethyl corticoids, their preparation and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-02-22 | — | — | EP | disclosed |