Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.61 |
| ▸ | PGR | P06401 | 7/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859043 | 1.00 | CYP3A4 (0.61) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL11246597 | 0.92 | PGR (0.70) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL11127297 | 0.92 | PGR (0.70) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL11246599 | 0.92 | PGR (0.70) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL9807832 | 0.92 | PGR (0.54) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL9807826 | 0.92 | PGR (0.54) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL10427789 | 0.91 | PGR (0.64) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL10427790 | 0.91 | PGR (0.64) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL7596820 | 0.89 | PGR (0.61) | CYP3A4PGRNR3C1HIF1AABCB11 | |
| SCHEMBL11122100 | 0.88 | PGR (0.69) | CYP3A4PGRNR3C1HIF1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835724-B2 | Topical antiinflammatory agents for treating inflammatory dermatoses | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-28 | — | — | US | disclosed |
| US-20020103392-A1 | CORTICOID-17,21-DICARBOXYLIC ESTERS AND CORTICOSTEROID 17-CARBOXYLIC ESTER 21-CARBONIC ESTERS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103392-A1 | CORTICOID-17,21-DICARBOXYLIC ESTERS AND CORTICOSTEROID 17-CARBOXYLIC ESTER 21-CARBONIC ESTERS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THESE COMPOUNDS | NR3C1, HSD3B1, HSD17B7 | CYP3A4 246/4885PGR 707/4885NR3C1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.