Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133622 | 0.78 | MEN1 (0.64) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL13184564 | 0.77 | TAAR1 (0.57) | SIGMAR1TSHR | |
| Ammonia Solution, Strong SCHEMBL16268586 | 0.77 | MEN1 (0.61) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL1829643 | 0.76 | MEN1 (0.55) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL4502698 | 0.74 | MEN1 (0.70) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL8851564 | 0.74 | KMT2A (0.57) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL6422921 | 0.74 | KMT2A (0.63) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL8749866 | 0.74 | MEN1 (0.57) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL8944637 | 0.74 | SIGMAR1 (0.68) | MEN1KMT2ATDP1MAOACHRM2 | |
| SCHEMBL1833549 | 0.73 | MEN1 (0.52) | MEN1KMT2ATDP1MAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4524073-A | β-Lactam compounds | BEECHAM GROUP P.1.C. (GB) | 1985-06-18 | — | — | US | disclosed |
| EP-0101199-A1 | Beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1984-02-22 | — | — | EP | disclosed |