Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 3/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2673394 | 0.83 | ALDH1A1 (0.50) | EPHX2MAPTNPC1ALDH1A1CYP1A2 | |
| SCHEMBL27320801 | 0.82 | EPHX2 (0.47) | EPHX2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL12617736 | 0.80 | NPC1 (0.60) | MAPTRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL7325136 | 0.79 | KMT2A (0.49) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27321194 | 0.79 | ALDH1A1 (0.45) | MAPTRAB9ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL3344661 | 0.79 | EPHX2 (0.47) | EPHX2MAPTNPC1ALDH1A1CYP1A2 | |
| SCHEMBL5706013 | 0.79 | TDP1 (0.47) | EPHX2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL28176880 | 0.78 | EPHX2 (0.50) | EPHX2ALDH1A1MEN1KMT2AMAOA | |
| SCHEMBL11203242 | 0.78 | TDP1 (0.55) | EPHX2MAPTNPC1ALDH1A1L3MBTL1 | |
| SCHEMBL7060682 | 0.78 | MMP8 (0.56) | RAB9ANPC1ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050671-B1 | THIAZOLO(3,2-A)PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING SAME, AND DRUG CONTAINING SAME | TEIJIN LIMITED (JP) | 1985-03-20 | — | — | EP | disclosed |
| US-4383996-A | IMMUNOREGULATOR | TEIJIN LIMITED (JP) | 1983-05-17 | — | — | US | disclosed |
| EP-0050671-A1 | THIAZOLO(3,2-a)PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING SAME, AND DRUG CONTAINING SAME | TEIJIN LIMITED (JP) | 1982-05-05 | — | — | EP | disclosed |