Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965545 | 0.88 | MTNR1A (0.43) | MTNR1A | |
| SCHEMBL10963524 | 0.84 | MAPT (0.46) | PIN1PKMMAPTPOLBTP53 | |
| SCHEMBL10964778 | 0.80 | MAPT (0.46) | MTNR1APIN1MAPTTP53PTPN1 | |
| SCHEMBL10963320 | 0.80 | KEAP1 (0.49) | PIN1PKMMAPTTP53PTPN1 | |
| SCHEMBL10964341 | 0.80 | MTNR1A (0.47) | MTNR1APIN1MAPTPTPN1PTPN2 | |
| SCHEMBL10894281 | 0.76 | PKM (0.54) | PIN1PKMMAPTPOLBPTPN1 | |
| SCHEMBL10967884 | 0.74 | PTPN1 (0.35) | PIN1MAPTTP53PTPN1PTPRF | |
| SCHEMBL10964318 | 0.72 | MAPT (0.45) | PKMMAPTPOLBTP53 | |
| SCHEMBL10895783 | 0.72 | MTNR1A (0.46) | MTNR1AMAPTTP53NPC1RAB9A | |
| SCHEMBL10962652 | 0.71 | PTPN1 (0.35) | PIN1MAPTTP53PTPN1PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | claimed |
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |