Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10889889 | 0.99 | PTPN1 (0.34) | PTPN1PTPN2PIN1CDC7PLK4 | |
| SCHEMBL10967884 | 0.97 | PTPN1 (0.35) | PTPN1PTPN2PIN1CDC7PLK4 | |
| SCHEMBL10964005 | 0.75 | PTPN1 (0.35) | PTPN1PTPN2GPR35NPC1RAB9A | |
| SCHEMBL10963524 | 0.75 | MAPT (0.46) | PTPN1PTPN2PIN1GPR35NPC1 | |
| SCHEMBL10963320 | 0.74 | KEAP1 (0.49) | PTPN1PIN1GPR35MAPTLMNA | |
| SCHEMBL10964778 | 0.74 | MAPT (0.46) | PTPN1PTPN2PIN1NPC1RAB9A | |
| SCHEMBL11390974 | 0.73 | LMNA (0.43) | GPR35NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10967347 | 0.73 | PTPN1 (0.35) | PTPN1PTPN2NPC1RAB9AMEN1 | |
| SCHEMBL10894281 | 0.73 | PKM (0.54) | PTPN1PTPN2PIN1GPR35NPC1 | |
| SCHEMBL10964341 | 0.71 | MTNR1A (0.47) | PTPN1PTPN2PIN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | claimed |
| EP-0159964-A2 | 3-Substituted thiopyrone | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |