Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10965609 | 0.89 | ALDH1A1 (0.46) | KDM4EALDH1A1HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10914569 | 0.89 | ALDH1A1 (0.48) | KDM4EALDH1A1HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10915699 | 0.88 | SIGMAR1 (0.49) | KDM4EALDH1A1HTR1AADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10972048 | 0.87 | KDM4E (0.47) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10970085 | 0.86 | ALDH1A1 (0.46) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10971146 | 0.86 | CCR5 (0.46) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL10970591 | 0.85 | ALDH1A1 (0.47) | KDM4EALDH1A1SIGMAR1SLC18A3DRD2 | |
| Hydrochloric Acid SCHEMBL10967357 | 0.84 | ALDH1A1 (0.47) | KDM4EALDH1A1SIGMAR1SLC18A3DRD2 | |
| Hydrochloric Acid SCHEMBL10970332 | 0.84 | LIPG (0.45) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10917762 | 0.83 | PDE3B (0.51) | KDM4EALDH1A1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064706-B1 | 5-(4-PHENYL-1-PIPERIDINYL)METHYL-2,3-DIHYDRO-2-OXO-1H-IMIDAZOLE-4-CARBOXYLIC ACID DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-03 | — | — | EP | claimed |
| JP-57185280-A | — | — | None | — | — | JP | disclosed |
| EP-0064706-B1 | 5-(4-PHENYL-1-PIPERIDINYL)METHYL-2,3-DIHYDRO-2-OXO-1H-IMIDAZOLE-4-CARBOXYLIC ACID DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1985-07-03 | — | — | EP | disclosed |
| EP-0064706-A1 | 5-(4-Phenyl-1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |
| JP-S57185280-A | 5-(4-PHENYL-1-PIPERIDINYL)METHYL-2,3-DIHYDRO- 2-OXO-1H-IMIDAZOLE-4-CARBOXYLIC ACID DERIVATIVES | MERRELL DOW PHARMA | 1982-11-15 | — | — | JP | disclosed |
| US-4329470-A | CORDIOTONIC, HYPOTENSIVE, ANTITHROMBOSIS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-05-11 | — | — | US | disclosed |