Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10841687 | 0.86 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| Water SCHEMBL10842574 | 0.85 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| SCHEMBL8083425 | 0.85 | LMNA (0.70) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| Ibafloxacin SCHEMBL10073765 | 0.84 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| Ibafloxacin SCHEMBL29465687 | 0.84 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| Ibafloxacin SCHEMBL154637 | 0.84 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| SCHEMBL10784346 | 0.83 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| SCHEMBL10785119 | 0.83 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| SCHEMBL10782548 | 0.83 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT | |
| Water SCHEMBL10788704 | 0.82 | LMNA (0.67) | LMNAKDM4ESMN1; SMN2CYP1A2AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079162-B1 | DERIVATIVES OF 8-AMINO AND 8-AMINOMETHYL BENZO(IJ)QUINOLIZINE | RIKER LABORATORIES, INCORPORATED (US) | 1986-07-23 | — | — | EP | disclosed |