Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 9/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL10842574 | 0.99 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL8083425 | 0.89 | LMNA (0.70) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| Ibafloxacin SCHEMBL154637 | 0.88 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| Ibafloxacin SCHEMBL29465687 | 0.88 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| Ibafloxacin SCHEMBL10073765 | 0.88 | LMNA (0.69) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10784346 | 0.87 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10785119 | 0.87 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10782548 | 0.87 | LMNA (0.68) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| Water SCHEMBL10788704 | 0.86 | LMNA (0.67) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL10967396 | 0.86 | LMNA (0.66) | LMNAKDM4ESMN1; SMN2CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3435976-B1 | ANTIBACTERIAL COMPOSITIONS | WOCKHARDT LTD (IN) | 2021-03-10 | — | — | EP | claimed |
| US-20180325879-A1 | Antibacterial compositions | WOCKHARDT LIMITED (IN) | 2018-11-15 | — | — | US | claimed |
| US-20140296280-A1 | PURES-(-)-9-FLUORO-6,7-DIHYDRO-8-(4-HYDROXYPIPERIDIN-1-YL)-5-METHYL-1-OXO-1H,-5H-BENZO[I,J]QUINOLIZINE-2- CARBOXYLIC ACID L-ARGININE SALT TETRAHYDRATE AND A PROCESS FOR ITS PREPARATION | GANGAKHEDKAR KIRAN KUMAR (IN) | 2014-10-02 | — | — | US | claimed |
| EP-2776433-A1 | PURES-(-)-9-FLUORO-6,7-DIHYDRO-8-(4-HYDROXYPIPERIDIN-1-YL)-5-METHYL-1-OXO-1H,-5H-BENZO[I,J]QUINOLIZINE-2- CARBOXYLIC ACID L-ARGININE SALT TETRAHYDRATE AND A PROCESS FOR ITS PREPARATION | Wockhardt Limited (IN) | 2014-09-17 | — | — | EP | claimed |
| WO-2013046061-A1 | PURES-(-)-9-FLUORO-6,7-DIHYDRO-8-(4-HYDROXYPIPERIDIN-1-YL)-5-METHYL-1-OXO-1H,-5H-BENZO[I,J]QUINOLIZINE-2- CARBOXYLIC ACID L-ARGININE SALT TETRAHYDRATE AND A PROCESS FOR ITS PREPARATION | WOCKHARDT LIMITED (IN) | 2013-04-04 | — | — | WO | claimed |
| EP-0119779-A1 | 8-Alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acids | RIKER LABORATORIES, INCORPORATED (US) | 1984-09-26 | — | — | EP | claimed |
| US-4472407-A | Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu | RIKER LABORATORIES, INC. (US) | 1984-09-18 | — | — | US | claimed |
| EP-3435976-B1 | ANTIBACTERIAL COMPOSITIONS | WOCKHARDT LTD (IN) | 2021-03-10 | — | — | EP | disclosed |
| US-20180325879-A1 | Antibacterial compositions | WOCKHARDT LIMITED (IN) | 2018-11-15 | — | — | US | disclosed |
| US-20140296280-A1 | PURES-(-)-9-FLUORO-6,7-DIHYDRO-8-(4-HYDROXYPIPERIDIN-1-YL)-5-METHYL-1-OXO-1H,-5H-BENZO[I,J]QUINOLIZINE-2- CARBOXYLIC ACID L-ARGININE SALT TETRAHYDRATE AND A PROCESS FOR ITS PREPARATION | GANGAKHEDKAR KIRAN KUMAR (IN) | 2014-10-02 | — | — | US | disclosed |
| US-4568750-A | 1-ACETYL-5-BROMO-6-FLUORO-1,2,3,4-TETRAHYDROQUINALDINE | RIKER LABORATORIES, INC. (US) | 1986-02-04 | — | — | US | disclosed |
| EP-0119779-A1 | 8-Alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acids | RIKER LABORATORIES, INCORPORATED (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4472407-A | Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H-benzo[ij]qu | RIKER LABORATORIES, INC. (US) | 1984-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296280-A1 | PURES-(-)-9-FLUORO-6,7-DIHYDRO-8-(4-HYDROXYPIPERIDIN-1-YL)-5-METHYL-1-OXO-1H,-5H-BENZO[I,J]QUINOLIZINE-2- CARBOXYLIC ACID L-ARGININE SALT TETRAHYDRATE AND A PROCESS FOR ITS PREPARATION | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, Q6ZSR9, ARG1 | LMNA 1391/4885KDM4E 593/4885SMN1; SMN2 3035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.