Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 11/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853379 | 0.86 | ADORA2B (0.66) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL18399526 | 0.85 | ADORA2B (0.68) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL16120984 | 0.85 | ADORA2B (0.81) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL11539363 | 0.84 | ADORA2B (0.67) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL10858566 | 0.83 | LMNA (0.73) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL10768492 | 0.83 | LMNA (0.78) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL13944619 | 0.82 | LMNA (0.81) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL8697314 | 0.82 | LMNA (0.71) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL2925220 | 0.82 | LMNA (0.71) | ADORA2BLMNAMAPTSMN1; SMN2POLB | |
| SCHEMBL5265296 | 0.82 | LMNA (0.81) | ADORA2BLMNAMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049494-B1 | ESTERS OF 7-HYDROXYALKYL-1,3-DIMETHYL XANTHINES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS LIPID DIMINISHERS | King Consult GmbH (DE) | 1985-04-17 | — | — | EP | disclosed |