Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022229 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KMT2ARECQLCA2CA9 | |
| SCHEMBL7874157 | 0.82 | KMT2A (0.71) | ALDH1A1KMT2A | |
| SCHEMBL10972068 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2ARECQLCA2CA9 | |
| SCHEMBL11452472 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KMT2ACA2CA9CA12 | |
| Methyl Aminolevulinate SCHEMBL1177327 | 0.78 | LMNA (0.56) | ALDH1A1KMT2AMAPTHSD17B10 | |
| SCHEMBL8779427 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KMT2ACA2CA9CA12 | |
| SCHEMBL15341172 | 0.76 | HSD11B1 (0.70) | ALDH1A1KMT2ARECQLCA2CA9 | |
| SCHEMBL8379500 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KMT2ARECQLCA2CA9 | |
| SCHEMBL14684066 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KMT2ARECQLCA2CA9 | |
| SCHEMBL27777022 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063323-B1 | 5-SUBSTITUTED 4-OXO-PGI1 DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1985-10-30 | — | — | EP | disclosed |
| EP-0063323-A1 | 5-Substituted 4-oxo-PGI1 derivatives, their preparation and pharmaceutical compositions | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1982-10-27 | — | — | EP | disclosed |