Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452472 | 0.90 | ALDH1A1 (0.62) | KMT2ALMNAALDH1A1GAACYP3A4 | |
| SCHEMBL8779427 | 0.87 | ALDH1A1 (0.59) | KMT2ALMNAALDH1A1GAACYP3A4 | |
| SCHEMBL7874068 | 0.85 | POLB (0.59) | KMT2ALMNAALDH1A1POLBMAPK1 | |
| SCHEMBL7870908 | 0.85 | ALDH1A1 (0.62) | KMT2ALMNAALDH1A1GAAPOLB | |
| SCHEMBL7862213 | 0.85 | KMT2A (0.69) | KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7874047 | 0.85 | KMT2A (0.53) | KMT2ALMNAALDH1A1GAAPOLB | |
| SCHEMBL28897130 | 0.85 | KMT2A (0.53) | KMT2ALMNAALDH1A1GAACYP2C19 | |
| SCHEMBL28101227 | 0.84 | MAPT (0.59) | KMT2ALMNA | |
| SCHEMBL16144557 | 0.83 | KMT2A (0.57) | KMT2ALMNAALDH1A1GAAPOLB | |
| SCHEMBL4022229 | 0.82 | ALDH1A1 (0.62) | KMT2ALMNAALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | claimed |
| CN-113307753-B | Preparation method of thioether derivative | 华侨大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-113307753-A | Preparation method of thioether derivative | 华侨大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-103232344-B | A kind of method of synthesizing S-2-methyl chloropropionate | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-103232344-A | Method for synthesizing S-2-methyl chloropropionate | UNIV NANJING SCIENCE & TECH | 2013-08-07 | — | — | CN | disclosed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |