Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787031 | 0.78 | NPC1 (0.47) | TDP1LMNANPC1L3MBTL1KMT2A | |
| SCHEMBL11513183 | 0.74 | NQO1 (0.36) | TDP1LMNAL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL27997482 | 0.74 | ALDH1A1 (0.35) | TDP1L3MBTL1PTGDR2GAAKMT2A | |
| SCHEMBL8009351 | 0.73 | — | — | |
| SCHEMBL2079650 | 0.72 | LMNA (0.47) | LMNANPC1HTTGAASMN1; SMN2 | |
| SCHEMBL11850996 | 0.72 | ALDH1A1 (0.36) | TDP1NPC1L3MBTL1HTTGAA | |
| SCHEMBL7997628 | 0.72 | PTPN1 (0.35) | TDP1L3MBTL1KMT2AMEN1USP2 | |
| SCHEMBL9998500 | 0.70 | LTA4H (0.35) | TDP1LMNANPC1L3MBTL1HTT | |
| SCHEMBL22650 | 0.69 | POLB (0.36) | LMNAL3MBTL1HTTGAASMN1; SMN2 | |
| SCHEMBL15069616 | 0.69 | ALDH1A1 (0.39) | LMNAGAATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075117-B1 | 2H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | disclosed |
| US-4428766-A | 2N-1,2,4,6,Thiatriazine-1,1-dioxides and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0075117-A2 | 2H-1,2,4,6-thiatriazine-1,1-dioxides, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-03-30 | — | — | EP | disclosed |
| US-4343648-A | 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES | BASF AKTIENGESELLSCHAFT (DE) | 1982-08-10 | — | — | US | disclosed |