Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491544 | 0.80 | TDP1 (0.49) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL10967749 | 0.78 | TDP1 (0.33) | NPC1KMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL9786979 | 0.77 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL8948941 | 0.74 | KMT2A (0.61) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9786976 | 0.73 | MAPT (0.44) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL3599787 | 0.73 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9371798 | 0.73 | L3MBTL1 (0.63) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL13950675 | 0.73 | LMNA (0.57) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL5770727 | 0.73 | L3MBTL1 (0.60) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL3732530 | 0.71 | NPC1 (0.69) | NPC1RAB9AKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988662-A | MULTILAYER ELEMENT OF A COATED SUBSTRATE, A FILM WITH A COLOR-FORMING LACTONE, AN ACID AND A SENSITIZER | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1991-01-29 | — | — | US | disclosed |