Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576540 | 0.89 | CCR5 (0.39) | CCR5KCNH2 | |
| SCHEMBL1096776 | 0.84 | CCR5 (0.39) | CCR5KCNH2 | |
| SCHEMBL1097414 | 0.83 | CCR5 (0.37) | CCR5KCNH2 | |
| SCHEMBL1095976 | 0.80 | CCR5 (0.39) | CCR5 | |
| SCHEMBL1096396 | 0.77 | ESR1 (0.33) | CCR5KCNH2 | |
| SCHEMBL16274940 | 0.75 | CCR5 (0.44) | CCR5 | |
| SCHEMBL1105750 | 0.74 | CCR5 (0.40) | CCR5KCNH2 | |
| SCHEMBL1097192 | 0.74 | HTR2A (0.37) | CCR5 | |
| SCHEMBL1095663 | 0.74 | CCR5 (0.40) | CCR5KCNH2 | |
| SCHEMBL1096039 | 0.74 | DPP4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153658-B2 | Piperidine derivative or salt thereof | ASTELLAS PHARMA, INC. (JP) | 2012-04-10 | — | — | US | disclosed |