Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20366010 | 0.73 | CTSD (0.42) | DNM1CTSDHDAC3HDAC1HDAC2 | |
| SCHEMBL116791 | 0.72 | DNM1 (0.68) | DNM1PLA2G2CPLA2G10MEN1FAAH | |
| SCHEMBL115222 | 0.72 | DNM1 (0.68) | DNM1PLA2G2CPLA2G10MEN1FAAH | |
| SCHEMBL116473 | 0.72 | DNM1 (0.68) | DNM1PLA2G2CPLA2G10MEN1FAAH | |
| SCHEMBL19520081 | 0.72 | HDAC3 (0.50) | DNM1CTSDPLA2G2CHDAC3HDAC1 | |
| SCHEMBL24451088 | 0.71 | CTSD (0.41) | DNM1CTSDHDAC3HDAC1HDAC2 | |
| SCHEMBL11078228 | 0.71 | DNM1 (0.41) | DNM1CTSDHDAC3HDAC1HDAC2 | |
| SCHEMBL10969007 | 0.71 | DNM1 (0.41) | DNM1CTSDHDAC3HDAC1HDAC2 | |
| SCHEMBL11538163 | 0.70 | CPB2 (0.33) | DNM1PLA2G2CDPP7DPP8DPP9 | |
| SCHEMBL13002248 | 0.70 | HDAC3 (0.48) | DNM1CTSDPLA2G2CHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046712-B1 | FLUORINATED DIAMINOBUTANE DERIVATIVES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1985-02-06 | — | — | EP | disclosed |
| US-4435425-A | INHIBITORS OF GAMMA-AMINOBUTYRIC ACID TRANSAMINASE | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-03-06 | — | — | US | disclosed |
| EP-0046712-A1 | Fluorinated diaminobutane derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-03-03 | — | — | EP | disclosed |