Etofylline Nicotinate

Etofylline Nicotinate

SCHEMBL1649975

Cn1c(=O)c2c(ncn2CCOC(=O)c2cccnc2)n(C)c1=O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 3/20 0.64
RXFP1 Q9HBX9 7/20 0.62
ALDH1A1 P00352 2/20 0.57
LMNA P02545 3/20 0.56
GAA P10253 2/20 0.56
MAPK1 P28482 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11389921 0.91 LMNA (0.57) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL25295543 0.88 LMNA (0.56) ADORA2BRXFP1LMNAGAAMAPK1
SCHEMBL30563571 0.88 LMNA (0.56) ADORA2BRXFP1LMNAGAAMAPK1
SCHEMBL30563533 0.87 LMNA (0.56) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL25292741 0.87 LMNA (0.56) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL25248642 0.86 LMNA (0.54) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL30563556 0.86 LMNA (0.54) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL10970100 0.85 LMNA (0.64) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL25248797 0.85 LMNA (0.49) ADORA2BRXFP1ALDH1A1LMNAGAA
SCHEMBL30563550 0.85 LMNA (0.49) ADORA2BRXFP1ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1079650-A The new purposes of nicotinic acid and derivant thereof QIU BOLING (CN) 1993-12-22 CN claimed
US-12551475-B2 Methods and compositions for treating RNA viral infections MODEL MEDICINES, INC. (US) 2026-02-17 US disclosed
EP-4667008-A2 METHODS AND COMPOSITIONS FOR TREATING RNA VIRAL INFECTIONS Model Medicines, Inc. (US) 2025-12-24 EP disclosed
US-20250066413-A1 COMPOSITIONS FOR TREATMENT OF INFLAMMATION METRO INTERNATIONAL BIOTECH, LLC 2025-02-27 US disclosed
EP-4452279-A1 COMPOSITIONS FOR TREATMENT OF INFLAMMATION Metro International Biotech, LLC (US) 2024-10-30 EP disclosed
CN-118541157-A Composition for treating inflammation 麦德龙国际生物科技有限责任公司 2024-08-23 CN disclosed
CN-117805308-A Processing method of chromatographic off-machine data and related application thereof 四川帕诺米克生物科技有限公司 2024-04-02 CN disclosed
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FIRST WAVE BIO, INC. 2024-03-07 US disclosed
US-11878994-B1 Compositions for treatment of inflammation METRO INTERNATIONAL BIOTECH, LLC (US) 2024-01-23 US disclosed
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FIRST WAVE BIO, INC. (US) 2023-10-24 US disclosed
US-20110171195-A1 METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP DUKE UNIVERSITY (US) 2011-07-14 US disclosed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-20100239667-A1 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR PROLONGED EFFECT EGALET A/S (DK) 2010-09-23 US disclosed
US-20100227896-A1 USE OF VITAMIN PP COMPOUNDS ASTELLAS DEUTSCHLAND GMBH (DE) 2010-09-09 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed
EP-2155167-A2 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR PROLONGED EFFECT Egalet A/S (DK) 2010-02-24 EP disclosed
WO-2008157205-A2 METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP DUKE UNIVERSITY (US) 2008-12-24 WO disclosed
WO-2008148798-A2 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR PROLONGED EFFECT EGALET A/S (DK) 2008-12-11 WO disclosed
EP-1079832-B1 USE OF VITAMIN PP COMPOUNDS KLINGE CO CHEM PHARM FAB (DE) 2005-11-30 EP disclosed
EP-0532446-A1 Use of xanthines in the treatment or prevention of hypeoglycemia NOVO NORDISK A/S (DK) 1993-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074995-A1 METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES FH, CS, ECHS1 ADORA2B 3900/4885RXFP1 3046/4885ALDH1A1 2174/4885
US-12551475-B2 Methods and compositions for treating RNA viral infections SARS1, EIF2AK2, SNRPE ADORA2B 648/4885RXFP1 2437/4885ALDH1A1 2656/4885
US-20110171195-A1 METHODS AND COMPOSITIONS FOR TREATING URINARY TRACT INFECTIONS USING AGENTS THAT MIMIC OR ELEVATE CYCLIC AMP PDE7A, PDE8A, PDE8B ADORA2B 1024/4885RXFP1 1782/4885ALDH1A1 1738/4885
US-20250066413-A1 COMPOSITIONS FOR TREATMENT OF INFLAMMATION NQO1, NAMPT, MPO ADORA2B 1104/4885RXFP1 2201/4885ALDH1A1 642/4885
US-11878994-B1 Compositions for treatment of inflammation NQO1, NAMPT, MPO ADORA2B 1104/4885RXFP1 2201/4885ALDH1A1 642/4885
US-20100227896-A1 USE OF VITAMIN PP COMPOUNDS PNPO, NAMPT, NAPRT ADORA2B 1559/4885RXFP1 4520/4885ALDH1A1 1385/4885
US-20100239667-A1 CONTROLLED RELEASE PHARMACEUTICAL COMPOSITIONS FOR PROLONGED EFFECT SI, GIPR, MLN ADORA2B 820/4885RXFP1 685/4885ALDH1A1 3424/4885
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FH, CS, ECHS1 ADORA2B 3962/4885RXFP1 2975/4885ALDH1A1 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.