Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970173 | 0.80 | MEN1 (0.50) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL8210570 | 0.79 | ALOX5 (0.46) | ALOX5ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL13502464 | 0.79 | TSPO (0.64) | ALDH1A1LMNAHPGDKDM4ENPC1 | |
| SCHEMBL12676876 | 0.77 | MEN1 (0.51) | ALDH1A1LMNAMAPTHPGDKDM4E | |
| SCHEMBL3588874 | 0.77 | TSPO (0.62) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL6567506 | 0.74 | ALDH1A1 (0.49) | ALOX5ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9335770 | 0.74 | ALDH1A1 (0.46) | ALOX5ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL3585544 | 0.73 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL13502533 | 0.73 | TSHR (0.45) | ADORA3ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9511701 | 0.72 | ALOX5 (0.45) | ALOX5ADORA3ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122388-B1 | PROCESS FOR PREPARING VICINAL POLYCARBONYL COMPOUNDS | BASF Aktiengesellschaft (DE) | 1985-11-06 | — | — | EP | disclosed |
| EP-0122388-A1 | Process for preparing vicinal polycarbonyl compounds | BASF Aktiengesellschaft (DE) | 1984-10-24 | — | — | EP | disclosed |