Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252411 | 0.82 | FFAR1 (0.65) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL10967799 | 0.81 | SMN1; SMN2 (0.57) | GAA | |
| SCHEMBL2346349 | 0.81 | FFAR1 (0.62) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL3372818 | 0.81 | MAPT (0.62) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL10971280 | 0.81 | PARP15 (0.56) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL15647515 | 0.81 | MAPT (0.53) | MAPTALDH1A1KMT2AGAAMMP2 | |
| Lithium Ion SCHEMBL2346343 | 0.79 | MAPT (0.51) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL4114747 | 0.78 | RAB9A (0.55) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL2163526 | 0.78 | L3MBTL1 (0.57) | MAPTALDH1A1KMT2AGAAMMP2 | |
| SCHEMBL4284626 | 0.78 | MMP2 (0.71) | MAPTMMP2KDM4EMMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060119-B1 | AZETIDINONE COMPOUNDS AND THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| US-4500456-A | AND AZETIDINONE-4-SULFINIC ACID, OR SALT THEREOF | ELI LILLY AND COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0060120-B1 | PROCESS FOR PREPARING 4-HALOAZETIDIN-2-ONES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| EP-0019401-B1 | PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN | Lilly Industries Limited (GB) | 1984-03-21 | — | — | EP | disclosed |
| US-4368156-A | USING POSITIVE HALOGEN REAGENT | ELI LILLY AND COMPANY (US) | 1983-01-11 | — | — | US | disclosed |
| EP-0060119-A1 | Azetidinone compounds and their preparation | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |
| EP-0060120-A1 | Process for preparing 4-haloazetidin-2-ones | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4301280-A | Preparation of 3-substituted cephalosporins | LILLY INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |
| US-4176231-A | Process for preparing 3-exomethylenecepham sulfoxides | LILLY INDUSTRIES LIMITED (GB) | 1979-11-27 | — | — | US | disclosed |
| US-4133808-A | 4-(Formylthio)azetidinones and ozonization process therefor | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4052387-A | METHOD OF PREPARATION OF 3-METHYLENECEPHAMS | ELI LILLY AND COMPANY (US) | 1977-10-04 | — | — | US | disclosed |
| US-4048157-A | 4(Formylthio)-azetidin-2-ones and ozonization process therefor | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048160-A | Process for preparation of 7-alkoxy-3-bromomethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048163-A | Process for preparation of 7-alkoxy-3-chloromethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-4038275-A | PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS | ELI LILLY AND COMPANY (US) | 1977-07-26 | — | — | US | disclosed |