Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166603 | 0.79 | HPGD (0.54) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL29387256 | 0.79 | CYP3A4 (0.55) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL29425530 | 0.79 | HPGD (0.54) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL333141 | 0.79 | CYP3A4 (0.55) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL11528932 | 0.78 | GPR52 (0.61) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL11528927 | 0.78 | GPR52 (0.61) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL10669335 | 0.77 | CYP3A4 (0.59) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| SCHEMBL112406 | 0.77 | HPGD (0.57) | HPGDERCC5FEN1HTTSMN1; SMN2 | |
| Toluic Acid SCHEMBL148201 | 0.77 | ALDH1A1 (0.65) | HPGDERCC5FEN1SMN1; SMN2MYC | |
| Toluic Acid SCHEMBL6571818 | 0.77 | ALDH1A1 (0.65) | HPGDERCC5FEN1SMN1; SMN2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098934-B1 | 2-METHYLSELENO-BENZAMIDES | A. Nattermann & Cie. GmbH (DE) | 1985-12-27 | — | — | EP | disclosed |
| EP-0044453-B1 | NEW BENZISOSELENAZOLONES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1984-04-11 | — | — | EP | disclosed |
| EP-0098934-A1 | 2-Methylseleno-benzamides | A. Nattermann & Cie. GmbH (DE) | 1984-01-25 | — | — | EP | disclosed |
| US-4418069-A | Benzisoselenazolones and process for the treatment of rheumatic and arthritic diseases using them | A. NATTERMANN & CIE GMBH (DE) | 1983-11-29 | — | — | US | disclosed |
| EP-0044453-A2 | New benzisoselenazolones, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-01-27 | — | — | EP | disclosed |