Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554648 | 0.83 | PDCD1 (0.42) | PDCD1CD274ESR2ERBB2CYP2A6 | |
| SCHEMBL845280 | 0.82 | PDCD1 (0.44) | PDCD1CD274ESR2CYP2A6CYP2B6 | |
| SCHEMBL6027622 | 0.82 | PDCD1 (0.53) | PDCD1CD274ESR2CYP2A6CYP2B6 | |
| SCHEMBL29201425 | 0.81 | PDCD1 (0.41) | PDCD1CD274ESR2ERBB2CYP2A6 | |
| SCHEMBL10755148 | 0.81 | PDCD1 (0.43) | PDCD1CD274ESR2CYP2A6CYP2B6 | |
| SCHEMBL16359472 | 0.78 | PDCD1 (0.44) | PDCD1CD274ESR2ERBB2CYP2A6 | |
| SCHEMBL5501718 | 0.77 | ALDH1A1 (0.44) | ESR2CYP2A6ALDH1A1MAPK1TRPA1 | |
| SCHEMBL861566 | 0.77 | PTGS1 (0.51) | PDCD1CD274ESR2ALDH1A1MEN1 | |
| SCHEMBL2400343 | 0.74 | ESR2 (0.48) | PDCD1CD274ESR2CYP2A6CYP2B6 | |
| SCHEMBL30804714 | 0.74 | ESR2 (0.48) | PDCD1CD274ESR2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143153-A2 | Insecticidal 1,1'-Biphenyl -3-ylmethyl esters, their production and use and compositions containing them | FMC Corporation (US) | 1985-06-05 | — | — | EP | disclosed |