Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332105 | 0.82 | ADORA1 (0.44) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL14819131 | 0.79 | MAPT (0.47) | KMT2AMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL8622378 | 0.79 | APP (0.37) | KMT2ATSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL11334682 | 0.75 | CYP11B1 (0.43) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL19626595 | 0.72 | HTT (0.45) | KMT2AMAPTALDH1A1RXFP1MEN1 | |
| SCHEMBL29114755 | 0.70 | CBFB (0.43) | KMT2AMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL19625432 | 0.70 | MAPT (0.37) | KMT2AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10977740 | 0.69 | TOP1 (0.45) | KMT2AMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL17626033 | 0.69 | L3MBTL1 (0.36) | KMT2AMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL8618972 | 0.69 | TOP1 (0.44) | KMT2AMAPTPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4540790-A | COLORFORMERS INC PRESSURE SENSITIVE CARBONLESS DUPLICATION | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0061128-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM | STERLING DRUG INC. (US) | 1985-09-04 | — | — | EP | disclosed |
| US-4396767-A | COLORS, CARBONLESS DUPLICATION | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| EP-0061128-A1 | Pyridine compounds, process for their preparation and systems containing them | STERLING DRUG INC. (US) | 1982-09-29 | — | — | EP | disclosed |