Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961242 | 0.83 | ALDH1A1 (0.39) | S1PR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10997460 | 0.78 | S100B (0.50) | S1PR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11325858 | 0.78 | CSNK1D (0.44) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29114755 | 0.77 | CBFB (0.43) | S1PR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11332105 | 0.77 | ADORA1 (0.44) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL8622378 | 0.76 | APP (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL17626033 | 0.75 | L3MBTL1 (0.36) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL10972792 | 0.75 | KMT2A (0.42) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL19626595 | 0.74 | HTT (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL2960690 | 0.73 | ALDH1A1 (0.55) | CYP11B1CYP11B2S1PR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262078-A | SUBLIMABLE COLOR-FORMING PYRIDINE DERIVATIVE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1981-04-14 | — | — | US | disclosed |