SCHEMBL8622378

SCHEMBL8622378

CCOc1cc(N(CC)CC)ccc1-c1cc(-c2ccc(N(C)C)cc2)nc(-c2ccc(N(C)C)cc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 4/20 0.37
TERT O14746 1/20 0.37
MAPT P10636 4/20 0.36
LTB4R Q15722 1/20 0.36
SYK P43405 3/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
USP2 O75604 1/20 0.36
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.36
ADK P55263 1/20 0.36
PGR P06401 1/20 0.36
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11332105 0.89 ADORA1 (0.44) TERTMAPTLMNAMEN1KMT2A
SCHEMBL8660215 0.82 PGR (0.46) APPTERTMAPTSYKMEN1
SCHEMBL10972792 0.79 KMT2A (0.42) MAPTLMNAMEN1KMT2AMAPK1
SCHEMBL8617570 0.79 MAOB (0.47) MAPTLMNAMEN1KMT2AMAPK1
SCHEMBL8623343 0.78 LTB4R (0.43) APPTERTMAPTLTB4RSYK
SCHEMBL20237251 0.76 LMNA (0.46) APPMAPTLTB4RLMNAMEN1
SCHEMBL11334682 0.76 CYP11B1 (0.43) TERTMAPTLMNAMEN1KMT2A
SCHEMBL17255094 0.74 LTB4R (0.53) LTB4RMAPK1ADKRAB9AALDH1A1
SCHEMBL29430014 0.74 LTB4R (0.53) LTB4RMAPK1ADKRAB9AALDH1A1
SCHEMBL967279 0.73 ENPP1 (0.46) LTB4RSMN1; SMN2NPSR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085225-A1 METHOD FOR MANUFACTURING RECYCLED RESIN COMPOSITION 住友化学株式会社 2023-05-19 WO disclosed
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed
EP-0061128-B1 PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND SYSTEMS CONTAINING THEM STERLING DRUG INC. (US) 1985-09-04 EP disclosed
US-4446321-A COLOR FORMERS, CARBON-FREE DUPLICATION STERLING DRUG INC. (US) 1984-05-01 US disclosed
US-4363503-A FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS STERLING DRUG INC. (US) 1982-12-14 US disclosed
EP-0061128-A1 Pyridine compounds, process for their preparation and systems containing them STERLING DRUG INC. (US) 1982-09-29 EP disclosed