Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.49 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.49 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.49 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972919 | 0.83 | GAA (0.48) | AKR1B1NAMPTHSD11B1HTR6HTR2A | |
| SCHEMBL1992954 | 0.82 | POLB (0.44) | ABCC9ABCC8KCNJ11KCNJ8NAMPT | |
| SCHEMBL2462163 | 0.81 | KIF18A (0.61) | AKR1B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL776300 | 0.81 | HTR2A (0.54) | AKR1B1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL1990346 | 0.79 | HTR6 (0.49) | ABCC9ABCC8KCNJ11KCNJ8HTR6 | |
| SCHEMBL5618102 | 0.79 | HSD11B1 (0.51) | AKR1B1HSD11B1PTGDR2 | |
| SCHEMBL1533672 | 0.79 | HSD11B1 (0.60) | AKR1B1KIF18ANAMPTHSD11B1POLB | |
| SCHEMBL12527297 | 0.79 | ABCC9 (0.49) | ABCC9ABCC8KCNJ11KCNJ8KIF18A | |
| SCHEMBL16810 | 0.79 | HSD11B1 (0.57) | ABCC9ABCC8KCNJ11KCNJ8KIF18A | |
| SCHEMBL10969364 | 0.79 | TSHR (0.54) | ABCC9ABCC8KCNJ11KCNJ8NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554381-A | BORON TRIFLUORIDE, HYDROFLUORIC ACID | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1985-11-19 | — | — | US | disclosed |