Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877085 | 0.89 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL11671060 | 0.85 | MAPK1 (0.73) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL5164301 | 0.85 | CA1 (0.66) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL8837359 | 0.84 | ALDH1A1 (0.79) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL6049724 | 0.83 | CA1 (0.62) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL972717 | 0.82 | CA1 (0.67) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL851431 | 0.82 | CA1 (0.67) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL16859705 | 0.81 | ALDH1A1 (0.70) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL18730273 | 0.81 | CA1 (0.65) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA | |
| SCHEMBL955844 | 0.81 | CA1 (0.70) | ALDH1A1HSD17B10MAPK1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765844-B1 | PURINE NUCLEOTIDE DERIVATIVES | SOLVELL AS (NO) | 2014-07-30 | — | — | EP | disclosed |
| US-8153609-B2 | Purine nucleotide derivatives | LAURAS AS (NO) | 2012-04-10 | — | — | US | disclosed |
| US-20080293665-A1 | Purine Nucleotide Derivatives | LAURAS AS (NO) | 2008-11-27 | — | — | US | disclosed |
| WO-1989007108-A1 | PROCESS FOR PRODUCING NUCLEOSIDE-3',5'-CYCLOPHOSPHATES AND NUCLEOSIDE-3',5'-CYCLOTHIOPHOSPHATES | JASTORFF BERND (DE) | 1989-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293665-A1 | Purine Nucleotide Derivatives | CGAS, PDE8A, PDE7A | ALDH1A1 3225/4885HSD17B10 4521/4885MAPK1 1620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.