Sugi Predict

Sugi Predict / Compounds / SCHEMBL851431

SCHEMBL851431

SCHEMBL851431

O=[N+]([O-])c1ccc(OP(=O)(Cl)Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.67
▸ CA2 P00918 3/20 0.67
▸ CES2 O00748 1/20 0.67
▸ CES1 P23141 1/20 0.67
▸ ACHE P22303 2/20 0.57
▸ BCHE P06276 1/20 0.57
▸ ALDH1A1 P00352 5/20 0.56
▸ HSD17B10 Q99714 3/20 0.56
▸ MAPK1 P28482 3/20 0.56
▸ CYP3A4 P08684 2/20 0.56
▸ LMNA P02545 2/20 0.56
▸ TP53 P04637 1/20 0.56
▸ THRB P10828 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ TSHR P16473 1/20 0.51
▸ HSPB1 P04792 1/20 0.48
▸ CA9 Q16790 1/20 0.47
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18730273 0.98 CA1 (0.65) CA1CA2CES2CES1ACHE
SCHEMBL972717 0.88 CA1 (0.67) CA1CA2CES2CES1ACHE
SCHEMBL9316829 0.85 CES2 (0.68) CA1CA2CES2CES1ACHE
SCHEMBL6049724 0.85 CA1 (0.62) CA1CA2CES2CES1ACHE
SCHEMBL972719 0.85 CA1 (0.73) CA1CA2CES2CES1ACHE
SCHEMBL35319 0.83 CA1 (0.71) CA1CA2CES2CES1ACHE
SCHEMBL8877085 0.82 ALDH1A1 (0.64) CA1CA2CES2CES1ACHE
SCHEMBL1097455 0.82 ALDH1A1 (0.64) CA1CA2CES2CES1ACHE
SCHEMBL18089635 0.82 CA1 (0.59) CA1CA2CES2CES1ACHE
SCHEMBL8427162 0.82 ALDH1A1 (0.63) CA1CA2CES2CES1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118755478-A Efficient acid soil conditioner and preparation method thereof 江西禾锦农业科技有限公司 2024-10-11 — — CN claimed
US-8614312-B2 Method for preparing nucleotides and related analogues by synthesis on soluble substrate, and biological tools thus prepared CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-12-24 — — US claimed
US-20110118454-A1 METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2011-05-19 — — US claimed
EP-2265624-A1 METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED Centre National de la Recherche Scientifique (FR) 2010-12-29 — — EP claimed
WO-2009115694-A1 METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-09-24 — — WO claimed
US-5665802-A REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-09-09 — — US claimed
JP-6228169-A — — None — — JP disclosed
CN-122080069-A Phospholipid compounds and uses thereof — 2026-05-26 — — CN disclosed
EP-4744667-A2 EFFICIENT AND SCALABLE SYNTHESES OF NICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, PHOSPHORYLATED ANALOGS THEREOF, ADENYLYL DINUCLEOTIDE CONJUGATES THEREOF, AND NOVEL CRYSTALLINE FORMS THEREOF The Queen's University Of Belfast (GB) 2026-05-20 — — EP disclosed
US-20260115216-A1 NUCLEIC ACID PRECURSOR KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2026-04-30 — — US disclosed
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 — — US disclosed
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-02-05 — — US disclosed
EP-4658663-A2 PRODRUGS OF 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS Merck Sharp & Dohme LLC (US) 2025-12-10 — — EP disclosed
US-4152347-A REINFORCING AGENTS IN VULCANIZABLE RUBBER MIXTURES WHICH CONTAIN A SILICA FILLER DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-01 — — US disclosed
US-4144394-A FLAME RETARDANTS FOR POLYMERS MONSANTO COMPANY (US) 1979-03-13 — — US disclosed
US-4134877-A Flame retardant phosphoramidate compositions MONSANTO COMPANY (US) 1979-01-16 — — US disclosed
US-4124400-A Flame retardant polymer compositions MONSANTO COMPANY (US) 1978-11-07 — — US disclosed
US-4086302-A FLAME RETARDANTS MONSANTO COMPANY (US) 1978-04-25 — — US disclosed
US-4062909-A FIRE RETARDANTS MONSANTO COMPANY (US) 1977-12-13 — — US disclosed
US-3965220-A AMINE CATALYST MONSANTO COMPANY (US) 1976-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 CA1 4447/4885CA2 3731/4885CES2 1167/4885
US-20260115216-A1 NUCLEIC ACID PRECURSOR NSUN2, POLRMT, SSU72 CA1 1789/4885CA2 330/4885CES2 1635/4885
US-20110118454-A1 METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED PNP, NUDT1, DUT CA1 3158/4885CA2 4552/4885CES2 2592/4885
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF PNP, SLC28A1, SLC29A1 CA1 1691/4885CA2 356/4885CES2 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.