Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.70 |
| ▸ | CA2 | P00918 | 3/20 | 0.70 |
| ▸ | CES1 | P23141 | 2/20 | 0.70 |
| ▸ | CES2 | O00748 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28841894 | 0.85 | CA1 (0.66) | CA1CA2CES1CES2ALDH1A1 | |
| SCHEMBL5164301 | 0.85 | CA1 (0.66) | CA1CA2CES1CES2ALDH1A1 | |
| SCHEMBL8837359 | 0.84 | ALDH1A1 (0.79) | CA1CA2CES1CES2ALDH1A1 | |
| P-Nitrophenylphosphate SCHEMBL28027358 | 0.82 | CA1 (1.00) | CA1CA2CES1CES2ALDH1A1 | |
| SCHEMBL223704 | 0.82 | CES1 (1.00) | CA1CA2CES1CES2ALDH1A1 | |
| P-Nitrophenylphosphate SCHEMBL35320 | 0.82 | CA1 (1.00) | CA1CA2CES1CES2ALDH1A1 | |
| SCHEMBL1901209 | 0.82 | CA1 (0.62) | CA1CA2CES1CES2ALDH1A1 | |
| SCHEMBL28160072 | 0.82 | MAPK1 (0.57) | CA1CA2CES1CES2ALDH1A1 | |
| Methane SCHEMBL11686999 | 0.81 | CES2 (0.60) | CA1CA2CES1CES2ALDH1A1 | |
| SCHEMBL27763951 | 0.81 | CA1 (0.60) | CA1CA2CES1CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082394-A | Synthesis method of tri (4-aminophenyl) thiophosphate | 杭州布朗生物医药科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| EP-0765120-A1 | SYNERGISTIC COMPOSITION | Novartis AG (CH) | 1997-04-02 | — | — | EP | claimed |
| EP-0736252-A2 | Synergistic compositions with diafenthiuron | CIBA-GEIGY AG (CH) | 1996-10-09 | — | — | EP | claimed |
| WO-1995033380-A1 | SYNERGISTIC COMPOSITION | CIBA-GEIGY AG (CH) | 1995-12-14 | — | — | WO | claimed |
| WO-1993022909-A1 | INSECT TRAP | CIBA-GEIGY AG (CH) | 1993-11-25 | — | — | WO | claimed |
| EP-0022141-B2 | COMPOSITIONS AND METHODS FOR REDUCING HERBICIDAL INJURY | MONSANTO COMPANY (US) | 1987-12-02 | — | — | EP | claimed |
| US-4285720-A | Encapsulation process and capsules produced thereby | STAUFFER CHEMICAL COMPANY (US) | 1981-08-25 | — | — | US | claimed |
| US-4140516-A | Encapsulation process employing phase transfer catalysts | STAUFFER CHEMICAL COMPANY (US) | 1979-02-20 | — | — | US | claimed |
| US-20240058768-A1 | MEMBRANE FOR WATER FILTRATION | AQUAPORIN A/S (DK) | 2024-02-22 | — | — | US | disclosed |
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | SEATTLE CHILDREN’S HOSPITAL DBA SEATTLE CHILDREN’S RES INSTITUTE (US) | 2023-10-12 | — | — | US | disclosed |
| CN-116745025-A | membrane for water filtration | 水通道蛋白有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |
| US-11649288-B2 | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | SEATTLE CHILDREN'S HOSPITAL (US) | 2023-05-16 | — | — | US | disclosed |
| EP-0001753-B1 | THIOPHOSPHORIC(PHOSPHONIC) ACID ESTERS, PROCESS FOR THEIR PREPARATION AND USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4140516-A | Encapsulation process employing phase transfer catalysts | STAUFFER CHEMICAL COMPANY (US) | 1979-02-20 | — | — | US | disclosed |
| US-4073896-A | Insecticide from dimethylmuconic acid | SUN VENTURES, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4058605-A | Insecticides from dimethylmuconic acid | SUN VENTURES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3761589-A | PESTICIDAL PHOSPHOROTHIOATE COMPOSITIONS AND METHODS OF PREPARING THEM | BALCHEM CORP | 1973-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649288-B2 | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | PHOSPHO1, LCAT, CD47 | CA1 636/4885CA2 1735/4885CES1 527/4885 |
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | PHOSPHO1, LCAT, CD47 | CA1 636/4885CA2 1735/4885CES1 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.