Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 11/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28475673 | 0.72 | TSHR (0.39) | TSHRTHRBOPRM1FDPSGGPS1 | |
| SCHEMBL1269092 | 0.70 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL18584349 | 0.70 | TSHR (0.37) | TSHRTHRBOPRM1FDPSGGPS1 | |
| SCHEMBL3048556 | 0.70 | TSHR (0.44) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL203543 | 0.70 | OPRM1 (0.32) | TSHRTHRBOPRM1FDPSGGPS1 | |
| SCHEMBL11807889 | 0.69 | TSHR (0.50) | TSHRTHRBFDPSGGPS1SMPD1 | |
| SCHEMBL641208 | 0.68 | FDPS (0.41) | TSHRTHRBOPRM1FDPSGGPS1 | |
| SCHEMBL19432796 | 0.68 | TSHR (0.42) | TSHRTHRBFDPSGGPS1CES2 | |
| Ammonia Solution, Strong SCHEMBL6037107 | 0.68 | TSHR (0.35) | TSHRTHRBOPRM1FDPSGGPS1 | |
| SCHEMBL20609962 | 0.68 | TSHR (0.42) | TSHRTHRBFDPSGGPS1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021478-B1 | A PROCESS FOR THE STEREOSPECIFIC POLYMERIZATION OF AN ALPHA-OLEFIN AND AN ALPHA-OLEFIN POLYMERIZATION CATALYST SYSTEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1985-07-17 | — | — | EP | disclosed |
| US-4478989-A | TITANIUM TRIHALIDE AND REACTION PRODUCT OF ORGANOALUMINUM COMPOUND AND AROMATIC HYDROXY COMPOUND | SHELL OIL COMPANY (US) | 1984-10-23 | — | — | US | disclosed |
| EP-0021478-A1 | A process for the stereospecific polymerization of an alpha-olefin and an alpha-olefin polymerization catalyst system | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1981-01-07 | — | — | EP | disclosed |