SCHEMBL28475673

SCHEMBL28475673

CCCCCC(C(C)C)(C(C)C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
THRB P10828 1/20 0.39
OPRM1 P35372 1/20 0.38
FDPS P14324 11/20 0.36
GGPS1 O95749 7/20 0.36
CES2 O00748 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33
SMPD1 P17405 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3048556 0.97 TSHR (0.44) TSHRTHRBFDPSGGPS1CES2
SCHEMBL30110146 0.87
SCHEMBL21814237 0.79 TSHR (0.33) TSHRTHRBFDPSGGPS1CES2
SCHEMBL21814251 0.79 TSHR (0.33) TSHRTHRBFDPSGGPS1CES2
Hexane SCHEMBL580927 0.77 FDPS (0.39) TSHRTHRBFDPSGGPS1CES2
SCHEMBL1080648 0.77 FDPS (0.39) TSHRTHRBFDPSGGPS1CES2
SCHEMBL1269092 0.74 TSHR (0.44) TSHRTHRBFDPSGGPS1CES2
SCHEMBL18584349 0.74 TSHR (0.37) TSHRTHRBOPRM1FDPSGGPS1
SCHEMBL8638970 0.74 DNM1 (0.44) TSHRTHRBOPRM1FDPSGGPS1
SCHEMBL10975488 0.72 TSHR (0.35) TSHRTHRBOPRM1FDPSGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111727188-A Material for organic electroluminescent device 默克专利有限公司 2020-09-29 CN disclosed