Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | EEF2K | O00418 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10976806 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL9686029 | 0.81 | GABBR2 (0.47) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL23973921 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL47718 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL9159862 | 0.78 | TNFRSF1A (0.54) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL8495448 | 0.76 | ALOX5 (0.65) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL10786596 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| Hydrochloric Acid SCHEMBL11652316 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| Hydrochloric Acid SCHEMBL11652321 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1ALDH1A1GAALMNA | |
| SCHEMBL4448135 | 0.74 | LMNA (0.56) | SMN1; SMN2NPSR1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057881-B1 | AN ANTI-INFLAMMATORY, ANALGESIC, AND ANTIPYRETIC PHARMACEUTICAL COMPOSITION, AND METHOD FOR PRODUCING IT | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-12-04 | — | — | EP | disclosed |