Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.52 |
| ▸ | GLRB | P48167 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495448 | 0.84 | ALOX5 (0.65) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL47718 | 0.82 | SMN1; SMN2 (0.59) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL227202 | 0.82 | GLRA3 (0.63) | LMNARECQLCA2CA1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1943524 | 0.80 | GLRA3 (0.61) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL6136796 | 0.80 | LMNA (0.55) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL10001153 | 0.80 | LMNA (0.55) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL9355788 | 0.80 | GLRA3 (0.61) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL4257166 | 0.80 | LMNA (0.59) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL8659247 | 0.80 | GLRA3 (0.61) | LMNARECQLCA2CA1SMN1; SMN2 | |
| SCHEMBL9015699 | 0.80 | LMNA (0.55) | LMNARECQLCA2CA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007128672-A1 | SUBSTITUTED HEXAHYDRO-1,4-DIAZEPIN-5-ONES AND COMPOSITIONS STABILIZED THEREWITH | CIBA HOLDING INC. (CH) | 2007-11-15 | — | — | WO | claimed |
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | WOOD MERVIN G | 2007-11-08 | — | — | US | claimed |
| US-6905525-B2 | Candle wax stabilized with piperazinones | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-06-14 | — | — | US | claimed |
| US-6783913-B2 | POLYMERIC ACETAL RESIN CONTAINS UNITS (A), (B), (C), (D), AND (E). UNIT (A) IS A VINYL ALCOHOL UNIT. UNIT; (B) IS A POLYVINYL ACETAL UNIT CONTAINING AN R GROUP, WHERE R IS HYDROGEN, AN ALIPHATIC GROUP, AN AROMATIC GROUP, OR AN | KODAK POLYCHROME GRAPHICS LLC | 2004-08-31 | — | — | US | claimed |
| EP-1383832-A1 | STABILIZED CANDLE WAX | Ciba SC Holding AG (CH) | 2004-01-28 | — | — | EP | claimed |
| US-20030198887-A1 | Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing | EASTMAN KODAK COMPANY | 2003-10-23 | — | — | US | claimed |
| EP-1350801-A1 | Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing | Kodak Polychrome Graphics GmbH (DE) | 2003-10-08 | — | — | EP | claimed |
| US-6562084-B2 | Against discoloration and fading; also a UV absorber and/or an antioxidant | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-13 | — | — | US | claimed |
| US-6547840-B2 | White, dyed, dipped, unscented and/or scented candle wax is effectively stabilized against discoloration and fading by the incorporation of an imidazolidine in combination with a UV absorber and/or an antioxidant | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-04-15 | — | — | US | claimed |
| US-6544305-B2 | White, dyed, dipped, unscented and/or scented candle wax is effectively stabilized against discoloration and fading by the incorporation of an imidazolidine in combination with a UV absorber and/or an antioxidant | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-04-08 | — | — | US | claimed |
| US-6540795-B2 | Stabilized against discoloration and fading | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-04-01 | — | — | US | claimed |
| US-20030051392-A1 | CANDLE WAX STABILIZED WITH PIPERAZINDIONES | CIBA SPECIALTY CHEMICALS CORP. | 2003-03-20 | — | — | US | claimed |
| US-20030000128-A1 | Candle wax stabilized with oxazolidines | CIBA SPECIALTY CHEMICALS CORP. | 2003-01-02 | — | — | US | claimed |
| US-20030000130-A1 | Candle wax stabilized with piperazinones | CIBA SPECIALITY CHEMICALS CORP. | 2003-01-02 | — | — | US | claimed |
| US-20020194776-A1 | Candle wax stabilized with imidazolidines | CIBA SPECIALTY CHEMICALS CORP. | 2002-12-26 | — | — | US | claimed |
| US-20020194777-A1 | Candle wax stabilized with piperazinones | CIBA SPECIALTY CHEMICALS CORP. | 2002-12-26 | — | — | US | claimed |
| WO-2002079313-A1 | STABILIZED CANDLE WAX | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-10-10 | — | — | WO | claimed |
| EP-0585155-B1 | Trifluoromethylketone derivatives of peptides having HLE inhibiting activity, their preparation and pharmaceutical composition | ADIR (FR) | 1996-12-11 | — | — | EP | claimed |
| US-5565429-A | HUMAN LEUCOCYTE ELASTASE INHIBITORS; EMPHYSEMA; ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | claimed |
| EP-0585155-A1 | Trifluoromethylketone derivatives of peptides having HLE inhibiting activity, their preparation and pharmaceutical composition | ADIR ET COMPAGNIE (FR) | 1994-03-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070256352-A1 | Substituted hexahydro-1,4-diazepin-5-ones and compositions stabilized therewith | CRY1, GPX4, CAND1 | LMNA 2321/4885RECQL 1309/4885CA2 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.