SCHEMBL1097772

SCHEMBL1097772

COc1ccc2c(c1OC)N(C)C(=O)C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALDH1A1 P00352 7/20 0.46
POLB P06746 3/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
PRMT1 Q99873 1/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 1/20 0.44
CYP19A1 P11511 1/20 0.43
NQO2 P16083 1/20 0.43
BRD4 O60885 1/20 0.43
HSD17B10 Q99714 1/20 0.41
ACHE P22303 1/20 0.41
NFE2L2 Q16236 1/20 0.40
MAPK1 P28482 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
PABPC1 P11940 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11395236 0.83 RAB9A (0.44) RAB9ANPC1SMN1; SMN2ALDH1A1POLB
SCHEMBL11201120 0.77 KMT2A (0.61) SMN1; SMN2ALDH1A1POLBKMT2AMEN1
SCHEMBL1095849 0.75 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1POLBKMT2AMEN1
SCHEMBL27984382 0.72 RAB9A (0.46) RAB9ANPC1SMN1; SMN2ALDH1A1POLB
SCHEMBL25919801 0.72 ALDH1A1 (0.56) ALDH1A1POLBKMT2AMEN1KDM4E
SCHEMBL27984425 0.72 MAPT (0.38) RAB9ASMN1; SMN2ALDH1A1KDM4EHPGD
SCHEMBL12253692 0.70 RAB9A (0.76) RAB9ANPC1SMN1; SMN2ALDH1A1POLB
SCHEMBL21774714 0.67 CASP1 (0.52) ALDH1A1POLBKMT2AMEN1LMNA
SCHEMBL11040911 0.67 PRMT1 (0.67) ALDH1A1POLBKMT2AMEN1PRMT1
SCHEMBL9182912 0.67 TTR (0.52) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104190378-B Synthesis mycotoxin absorbant and preparation and the method using the synthesis mycotoxin absorbant 全技术公司 2017-06-09 CN claimed
CN-104190378-A SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH INC 2014-12-10 CN claimed
US-RE45274-E1 Synthetic mycotoxin adsorbents and methods of making and utilizing the same ALLTECH, INC. (US) 2014-12-02 US claimed
US-8426541-B2 Synthetic mycotoxin adsorbents and methods of making and utilizing the same ALLTECH, INC. (US) 2013-04-23 US claimed
US-20120214897-A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH, INC. (US) 2012-08-23 US claimed
EP-2470894-A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME Alltech, Inc. (US) 2012-07-04 EP claimed
CN-102549424-A Synthetic mycotoxin adsorbents and methods of making and using the same ALLTECH INC 2012-07-04 CN claimed
US-8153737-B2 Synthetic mycotoxin adsorbents and methods of making and utilizing the same ALLTECH, INC. (US) 2012-04-10 US claimed
WO-2011031562-A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH, INC. (US) 2011-03-17 WO claimed
US-20110054132-A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH, INC. (US) 2011-03-03 US claimed
EP-2470894-B1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH INC (US) 2021-12-29 EP disclosed
CN-105218393-B Synthesize mycotoxin absorbant and preparation and the method using the synthesis mycotoxin absorbant 全技术公司 2017-10-24 CN disclosed
CN-104190378-B Synthesis mycotoxin absorbant and preparation and the method using the synthesis mycotoxin absorbant 全技术公司 2017-06-09 CN disclosed
CN-102549424-B Synthetic mycotoxin adsorbents and methods of making and using the same ALLTECH, INC. (US) 2016-01-13 CN disclosed
CN-105218393-A The method of synthesis mycotoxin absorbant and preparation and the described synthesis mycotoxin absorbant of use ALLTECH INC 2016-01-06 CN disclosed
US-8153737-B2 Synthetic mycotoxin adsorbents and methods of making and utilizing the same ALLTECH, INC. (US) 2012-04-10 US disclosed
WO-2011031562-A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH, INC. (US) 2011-03-17 WO disclosed
US-20110054132-A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME ALLTECH, INC. (US) 2011-03-03 US disclosed
US-4261894-A Process for the preparation of optionally substituted 2,3-indolinediones SANDOZ, INC. (US) 1981-04-14 US disclosed
US-4212804-A Process for the preparation of optionally substituted 2,3-indolinediones SANDOZ, INC. (US) 1980-07-15 US disclosed