SCHEMBL10977883

SCHEMBL10977883

N=C1C(c2ccccc2)=CCc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.35
ALDH1A1 P00352 4/20 0.34
MAPK1 P28482 2/20 0.34
HTR6 P50406 1/20 0.34
PTPN1 P18031 2/20 0.32
PTPRC P08575 1/20 0.32
PTPRF P10586 1/20 0.32
CDC25B P30305 1/20 0.32
BACE1 P56817 1/20 0.32
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PRCP P42785 1/20 0.32
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29598333 0.84 ALDH1A1 (0.39) ALDH1A1MAPK1HTR6PTPN1PTPRC
SCHEMBL170839 0.84 ALDH1A1 (0.39) ALDH1A1MAPK1HTR6PTPN1PTPRC
SCHEMBL7549356 0.72 HTR6 (0.36) HTR6LMNA
SCHEMBL7960264 0.72 HTR6 (0.41) ALDH1A1MAPK1HTR6PTPRCTDP1
SCHEMBL6198719 0.71 ALDH1A1 (0.43) ALDH1A1MAPK1HTR6PTPRCNPC1
SCHEMBL27346062 0.70 ALDH1A1 (0.42) ALDH1A1MAPK1HTR6NPC1MAPT
SCHEMBL9441562 0.69 CYP3A4 (0.54) HTR6NPC1RAB9ASMN1; SMN2
SCHEMBL11537864 0.68 NPC1 (0.36) ALDH1A1MAPK1PTPN1PTPRCPTPRF
SCHEMBL2972504 0.68 TDP1 (0.42) ALDH1A1MAPK1PTPRCNPC1MAPT
SCHEMBL31414378 0.67 CYP3A4 (0.44) PTPN1MAPTCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069585-B1 COLOR-FORMING SULFONAMIDODIPHENYLAMINES, PHOTOGRAPHIC ELEMENTS CONTAINING THEM AND CORRESPONDING SULFONIMIDE DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-07-03 EP claimed
EP-0069585-A1 Color-forming sulfonamidodiphenylamines, photographic elements containing them and corresponding sulfonimide dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-12 EP claimed