SCHEMBL7960264

SCHEMBL7960264

BrC1=CCc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.41
ACHE P22303 1/20 0.38
MAOA P21397 3/20 0.37
CES1 P23141 2/20 0.37
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAOB P27338 2/20 0.34
BCHE P06276 1/20 0.34
TSHR P16473 2/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
PTPRC P08575 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2A6 P11509 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552234 0.84 CES1 (0.56) ACHEMAOACES1TDP1L3MBTL1
SCHEMBL8371987 0.78 CES1 (0.43) ACHEMAOACES1TDP1L3MBTL1
SCHEMBL32689461 0.78 CES1 (0.43) ACHEMAOACES1TDP1L3MBTL1
SCHEMBL21822872 0.75 CYP2A6 (0.45) MAOACES1TDP1L3MBTL1MAOB
SCHEMBL27807088 0.75 ALDH1A1 (0.47) CES1L3MBTL1BCHETSHRKMT2A
SCHEMBL4448887 0.74 HTR6 (0.41) HTR6ACHEMAOACES1MAOB
SCHEMBL6198719 0.73 ALDH1A1 (0.43) HTR6TDP1L3MBTL1MAOBTSHR
SCHEMBL170839 0.73 ALDH1A1 (0.39) HTR6TDP1PTPRCKMT2ACYP2A6
SCHEMBL29598333 0.73 ALDH1A1 (0.39) HTR6TDP1PTPRCKMT2ACYP2A6
SCHEMBL10977883 0.72 IDO1 (0.35) HTR6TDP1PTPRCKMT2ACYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772187-B Triphenylethylene derivative containing boron heterocycle and organic electroluminescent device containing triphenylethylene derivative 广东省大湾区华南理工大学聚集诱导发光高等研究院 2025-04-15 CN disclosed
US-20230263058-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-11678576-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2023-06-13 US disclosed
CN-115772187-A Triphenylethylene derivative containing boron heterocycle and organic electroluminescent device containing triphenylethylene derivative 广东省大湾区华南理工大学聚集诱导发光高等研究院 2023-03-10 CN disclosed
CN-115724834-A Indenoquinolinone or chromene quinolinone derivative and preparation method and application thereof 广东工业大学 2023-03-03 CN disclosed
CN-103833533-B A kind of preparation method of benzo [C] Fluorenone Basilea Pharmaceutica China Ltd. (CN) 2016-02-24 CN disclosed
US-8766248-B2 Nitrogen-containing aromatic compound, organic semiconductor material, and organic electronic device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-01 US disclosed
US-8766249-B2 Nitrogenated aromatic compound, organic semiconductor material, and organic electronic device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2014-07-01 US disclosed
US-20130184458-A1 NITROGENATED AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-07-18 US disclosed
US-20130150576-A1 NITROGEN-CONTAINING AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-06-13 US disclosed
US-6271395-B1 E.G.,(.+-.)-N-(2,3-DIHYDRO-2-(1-PYRROLIDINYL)-1H-INDEN-1-Y1) -2 ,4-DINITRO-N-METHYL-BENZENE-ACETAMIDE; STRONG AFFINITY FOR OPTICAL RECEPTORS, CENTRAL ANALGESIC, DIURETIC, ANTIARRYTHMIC, HYPOTENSIVE AND ANTIISCHEMIC ACTIVITY. HOECHST MARION ROUSSOL (FR) 2001-08-07 US disclosed
US-5157182-A Conversion of ortho-ethyltoluene to indene AMOCO CORPORATION (US) 1992-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263058-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT NR2E3, LGR4, NCOA4 HTR6 1654/4885ACHE 4436/4885MAOA 1880/4885
US-11678576-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, CYP1A1 HTR6 2249/4885ACHE 1269/4885MAOA 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.