Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308273 | 0.82 | HTR6 (0.40) | HTR6CA1CA2CES1MAOA | |
| Lithium SCHEMBL3684629 | 0.80 | HTR6 (0.39) | HTR6CA1CA2CES1MAOA | |
| SCHEMBL3684627 | 0.80 | HTR6 (0.39) | HTR6CA1CA2CES1MAOA | |
| SCHEMBL27596873 | 0.80 | HTR6 (0.39) | HTR6CA1CA2CES1MAOA | |
| SCHEMBL28209545 | 0.75 | HTR6 (0.36) | HTR6CA1CA2CES1MAOA | |
| SCHEMBL11060593 | 0.75 | SMN1; SMN2 (0.36) | HTR6LMNACA1CA2CES1 | |
| SCHEMBL396140 | 0.75 | MAOA (0.50) | LMNACES1MAOAS100A4ACHE | |
| SCHEMBL10977883 | 0.72 | IDO1 (0.35) | HTR6LMNA | |
| SCHEMBL7960264 | 0.70 | HTR6 (0.41) | HTR6CA1CA2CES1MAOA | |
| SCHEMBL28493380 | 0.68 | HTR6 (0.41) | HTR6LMNACES1MAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210305-A1 | TRANSFER HYDROGENATION PROCESS | Avecia Limited (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012574-A1 | TRANSFER HYDROGENATION PROCESS | AVECIA LIMITED (GB) | 2001-02-22 | — | — | WO | disclosed |