Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.56 |
| ▸ | CTSB | P07858 | 7/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10636541 | 0.97 | CTSL (0.59) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL10984447 | 0.91 | CTSL (0.53) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL10633448 | 0.87 | REN (0.56) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL7274809 | 0.86 | CAPN1 (0.60) | CTSLCTSBCAPN1 | |
| SCHEMBL10521374 | 0.86 | CAPN1 (0.48) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL10981376 | 0.86 | NMBR (0.60) | PSMB5CASP3CASP7 | |
| SCHEMBL10981144 | 0.85 | PSMB1 (0.52) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL10981150 | 0.85 | PSMB1 (0.52) | CTSLCTSBPSMB1PSMB5PSMB2 | |
| SCHEMBL7030418 | 0.85 | CTSL (0.50) | CTSLCTSBCTSS | |
| SCHEMBL1661198 | 0.84 | CTSL (0.57) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |