Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981150 | 1.00 | PSMB1 (0.52) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL10636524 | 0.91 | CTSK (0.54) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL10980392 | 0.90 | REN (0.54) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL10980358 | 0.90 | REN (0.54) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL10636541 | 0.88 | CTSL (0.59) | PSMB1PSMB5PSMB2CTSLCTSB | |
| SCHEMBL7274809 | 0.88 | CAPN1 (0.60) | CTSLCTSKCTSBCAPN1HTRA1 | |
| SCHEMBL10978997 | 0.86 | CTSK (0.50) | PSMB1PSMB5PSMB2CTSLCTSK | |
| SCHEMBL10978441 | 0.85 | CTSL (0.56) | PSMB1PSMB5PSMB2CTSLCTSB | |
| SCHEMBL10976835 | 0.85 | REN (0.56) | CTSLCTSBCAPN1REN | |
| SCHEMBL10976837 | 0.85 | REN (0.56) | CTSLCTSBCAPN1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4548926-A | RENIN INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1985-10-22 | — | — | US | disclosed |
| EP-0128762-A2 | New hypotensive peptides, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |