Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471664 | 0.86 | HPGD (0.66) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL30786345 | 0.86 | HPGD (0.66) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL10266907 | 0.84 | HPGD (0.64) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL29956989 | 0.83 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL24476677 | 0.82 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL22460629 | 0.82 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL20645627 | 0.82 | HPGD (0.54) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL24370814 | 0.82 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL15420246 | 0.81 | LMNA (0.51) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 | |
| SCHEMBL5703500 | 0.80 | HPGD (0.73) | HSP90AA1HSP90AB1HPGDMLYCDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143941-B | Synthesis method of intermediate of balusavir mefene | 北京四环制药有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-110143941-A | A kind of synthetic method of Barrow Sa Weimabo ester intermediate | 北京四环制药有限公司 | 2019-08-20 | — | — | CN | disclosed |
| US-8153674-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-04-10 | — | — | US | disclosed |
| CN-102245596-A | Quinazolinamide derivatives | MERCK PATENT GMBH | 2011-11-16 | — | — | CN | disclosed |
| US-20090182007-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-07-16 | — | — | US | disclosed |
| EP-2001866-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-12-17 | — | — | EP | disclosed |
| US-7297379-B2 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| WO-2007117982-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-10-18 | — | — | WO | disclosed |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182007-A1 | ORGANIC COMPOUNDS | REN, CYP17A1, HSD17B1 | HSP90AA1 1527/4885HSP90AB1 932/4885HPGD 269/4885 |
| US-20050255258-A1 | Polyfluorinated fused aromatics and their use in liquid-crystal mixtures | SCO2, CHRM1, CBR1 | HSP90AA1 4030/4885HSP90AB1 3922/4885HPGD 3247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.