SCHEMBL29956989

SCHEMBL29956989

CCN(CC)C(=O)c1ccc(F)c(B(O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 5/20 0.51
HSP90AB1 P08238 5/20 0.51
HPGD P15428 8/20 0.50
MLYCD O95822 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 4/20 0.48
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
BLM P54132 1/20 0.48
MAPT P10636 1/20 0.46
RAB9A P51151 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPC1 O15118 1/20 0.44
PKM P14618 1/20 0.44
CDK5 Q00535 1/20 0.44
CDK5R1 Q15078 1/20 0.44
PDK2 Q15119 1/20 0.43
ABCB11 O95342 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1097992 0.83 HSP90AA1 (0.57) HSP90AA1HSP90AB1HPGDMLYCDTDP1
SCHEMBL6522758 0.81 ERN1 (0.50) HSP90AA1HPGDALDH1A1SMN1; SMN2KMT2A
SCHEMBL30786345 0.77 HPGD (0.66) HSP90AA1HSP90AB1HPGDMLYCDTDP1
SCHEMBL471664 0.77 HPGD (0.66) HSP90AA1HSP90AB1HPGDMLYCDTDP1
SCHEMBL20645627 0.76 HPGD (0.54) HSP90AA1HSP90AB1HPGDMLYCDTDP1
SCHEMBL16599656 0.76 MLYCD (0.47) HPGDMLYCDALDH1A1LMNARAB9A
SCHEMBL29951662 0.76 MLYCD (0.47) HPGDMLYCDALDH1A1LMNARAB9A
SCHEMBL4037801 0.75 LMNA (0.50) ALDH1A1LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL841590 0.75 CES2 (0.42) HPGDALDH1A1LMNAMAPTRAB9A
SCHEMBL31224923 0.75 LMNA (0.50) ALDH1A1LMNAMAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed