Sugi Predict

Sugi Predict / Compounds / Bromide

Bromide

Bromide

SCHEMBL1098

[Br-].c1ccc(CCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.58
▸ GRIK1 P39086 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ SIGMAR1 Q99720 2/20 0.45
▸ MAOA P21397 1/20 0.45
▸ MAOB P27338 2/20 0.43
▸ HTR2A P28223 1/20 0.43
▸ KCNH2 Q12809 1/20 0.43
▸ HDAC3 O15379 2/20 0.42
▸ HDAC4 P56524 2/20 0.42
▸ HDAC1 Q13547 2/20 0.42
▸ HDAC7 Q8WUI4 2/20 0.42
▸ HDAC2 Q92769 2/20 0.42
▸ HDAC10 Q969S8 2/20 0.42
▸ HDAC11 Q96DB2 2/20 0.42
▸ HDAC8 Q9BY41 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3042031 0.94 HIF1A (0.56) HIF1AALDH1A1CYP1A2CYP2D6TSHR
Bromide SCHEMBL15766394 0.92 HIF1A (0.54) HIF1ASIGMAR1MAOAMAOB
Bromide SCHEMBL10996214 0.92 HIF1A (0.54) HIF1ASIGMAR1MAOAMAOB
Bromide SCHEMBL9442232 0.92 HIF1A (0.54) HIF1ASIGMAR1MAOAMAOB
SCHEMBL8376791 0.90 HIF1A (0.52) HIF1AGRIK1ALDH1A1CYP1A2CYP2D6
Iodide SCHEMBL3361577 0.89 HIF1A (0.56) HIF1ASIGMAR1MAOAMAOB
Hydrochloric Acid SCHEMBL30859404 0.88 HIF1A (0.54) HIF1ASIGMAR1MAOAMAOB
SCHEMBL8377196 0.87 HIF1A (0.48) HIF1AGRIK1ALDH1A1CYP1A2CYP2D6
SCHEMBL8604649 0.87 HIF1A (0.48) HIF1AGRIK1ALDH1A1CYP1A2CYP2D6
SCHEMBL8371256 0.87 HIF1A (0.48) HIF1AGRIK1ALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118652555-A Rare earth-based metal organic framework nanocomposite and preparation method and application thereof 哈尔滨工业大学 2024-09-17 — — CN disclosed
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 — — US disclosed
WO-2022133544-A1 CBD CANNABINOIDS AND CBD CANNABINOID ANALOGUES Botanix Pharmaceuticals Limited (AU) 2022-06-30 — — WO disclosed
WO-2021252640-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES, INC. (US) 2021-12-16 — — WO disclosed
US-10928728-B2 Photoactivable nitrogen bases BASF SE (DE) 2021-02-23 — — US disclosed
US-20210033972-A1 PHOTOACTIVABLE NITROGEN BASES BASF SE (DE) 2021-02-04 — — US disclosed
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES BASF SE (DE) 2018-08-02 — — US disclosed
US-9921477-B2 Photoactivable nitrogen bases BASE SE (DE) 2018-03-20 — — US disclosed
US-9624182-B2 Compounds as lysophosphatidic acid receptor antagonists AMIRA PHARMACEUTICALS, INC. (US) 2017-04-18 — — US disclosed
EP-2483252-B1 COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AMIRA PHARMACEUTICALS INC (US) 2017-03-08 — — EP disclosed
US-3983157-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-09-28 — — US disclosed
US-3980694-A ANTIULCER, ANTIAGGLOMERANTS, INCREASE OF NASAL PATENCY, LABOR INDUCEMENT, WOUND HEALINGPROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-09-14 — — US disclosed
US-3944595-A PROSTAGLANDIN THE UPJOHN COMPANY (US) 1976-03-16 — — US disclosed
US-3933895-A PROSTAGLANDINS, ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 — — US disclosed
US-3933896-A ANTICOAGULANTS, ASTHMA, LABOR INDUCERS, CERVICAL DILATION THE UPJOHN COMPANY (US) 1976-01-20 — — US disclosed
US-3933898-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 — — US disclosed
US-3933897-A ANTIULCER, ASTHMA, RENAL DYSFUNCTION THE UPJOHN COMPANY (US) 1976-01-20 — — US disclosed
US-3933899-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 — — US disclosed
US-3933900-A ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING THE UPJOHN COMPANY (US) 1976-01-20 — — US disclosed
US-3931289-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1976-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210033972-A1 PHOTOACTIVABLE NITROGEN BASES CBR1, ARNT, NR0B1 HIF1A 1258/4885GRIK1 1027/4885ALDH1A1 1659/4885
US-10928728-B2 Photoactivable nitrogen bases CBR1, NR0B1, NR0B2 HIF1A 1136/4885GRIK1 1010/4885ALDH1A1 1733/4885
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME ASNS, SI, NARS1 HIF1A 3307/4885GRIK1 2379/4885ALDH1A1 1286/4885
US-20180217498-A1 PHOTOACTIVABLE NITROGEN BASES CBR1, NR0B1, NR0B2 HIF1A 1136/4885GRIK1 1010/4885ALDH1A1 1733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.