Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.63 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.63 |
| ▸ | ABAT | P80404 | 1/20 | 0.63 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.63 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924101 | 0.93 | ALDH1A1 (0.63) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL1515911 | 0.92 | ALDH1A1 (0.69) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL15952644 | 0.88 | ALDH1A1 (0.63) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL2890759 | 0.86 | ALDH1A1 (0.73) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL14323012 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL972755 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL4855402 | 0.84 | ALDH1A1 (0.71) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL11503669 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL14856076 | 0.83 | ALDH1A1 (0.69) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL22160259 | 0.83 | FDPS (0.57) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153647-B2 | Aryl- and heteroaryl-ethyl-acylguanidine derivatives, their preparation and their application in therapeutics | SANOFI-AVENTIS (FR) | 2012-04-10 | — | — | US | disclosed |
| EP-2035401-B1 | ARYL- AND HETEROARYL-ETHYL-ACYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2011-02-23 | — | — | EP | disclosed |
| US-20090203696-A1 | Aryl- and Heteroaryl-Ethyl-Acylguanidine Derivatives, Their Preparation and Their Application in Therapeutics | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | US | disclosed |
| EP-2035401-A2 | ARYL- AND HETEROARYL-ETHYL-ACYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | Sanofi-Aventis (FR) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007144769-A2 | ARYL- AND HETEROARYL-ETHYL-ACYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203696-A1 | Aryl- and Heteroaryl-Ethyl-Acylguanidine Derivatives, Their Preparation and Their Application in Therapeutics | RAB9A, UGT1A9, CD59 | ALDH1A1 1212/4885HPGD 1490/4885TDP1 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.