SCHEMBL14323012

SCHEMBL14323012

CCCCCOc1cc(C=O)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.71
▸ TRIM24 O15164 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ ALDH5A1 P51649 1/20 0.58
▸ ABAT P80404 1/20 0.58
▸ TDP1 Q9NUW8 1/20 0.58
▸ TRIM33 Q9UPN9 1/20 0.58
▸ SMPD1 P17405 1/20 0.55
▸ FDPS P14324 1/20 0.51
▸ STK17B O94768 2/20 0.50
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ APP P05067 4/20 0.48
▸ TOP2A P11388 1/20 0.48
▸ AOX1 Q06278 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ PTGS2 P35354 1/20 0.46
▸ RAB9A P51151 1/20 0.46
▸ HTR1A P08908 1/20 0.45
▸ ALPI P09923 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11503669 0.98 ALDH1A1 (0.69) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL14856076 0.98 ALDH1A1 (0.69) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL2890759 0.95 ALDH1A1 (0.73) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL972755 0.90 ALDH1A1 (0.76) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL14790874 0.88 ALDH1A1 (0.64) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL5216212 0.88 ALDH1A1 (0.58) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL3842399 0.86 ALDH1A1 (0.57) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL13258617 0.86 ALDH1A1 (0.57) ALDH1A1TRIM24HPGDALDH5A1ABAT
SCHEMBL14953129 0.86 ALDH1A1 (0.57) ALDH1A1TRIM24HPGDALDH5A1ABAT
Protocatechualdehyde SCHEMBL6675611 0.86 ALDH1A1 (0.69) ALDH1A1TRIM24HPGDALDH5A1ABAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 — — US claimed
EP-2723841-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2017-01-04 — — EP claimed
US-20160186093-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2016-06-30 — — US claimed
US-9309487-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2016-04-12 — — US claimed
US-20140378360-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2014-12-25 — — US claimed
EP-2723841-A1 PERFUME SYSTEMS The Procter and Gamble Company (US) 2014-04-30 — — EP claimed
CN-103608444-A Perfume system PROCTER & GAMBLE 2014-02-26 — — CN claimed
US-20120329696-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2012-12-27 — — US claimed
WO-2012177357-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2012-12-27 — — WO claimed
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 — — US disclosed
US-20180037843-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2018-02-08 — — US disclosed
US-9822327-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2017-11-21 — — US disclosed
US-9822327-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2017-11-21 — — US disclosed
EP-2723841-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2017-01-04 — — EP disclosed
US-20140378360-A1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2014-12-25 — — US disclosed
US-8912350-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2014-12-16 — — US disclosed
US-8912350-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2014-12-16 — — US disclosed
US-20120329696-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2012-12-27 — — US disclosed
WO-2012177357-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY (US) 2012-12-27 — — WO disclosed
US-20120329696-A1 PERFUME SYSTEMS PROCTER & GAMBLE COMPANY, THE 2012-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037843-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 ALDH1A1 1292/4885TRIM24 4410/4885HPGD 400/4885
US-20120329696-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 ALDH1A1 1292/4885TRIM24 4410/4885HPGD 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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